Developing AHA ECC recommendation informed by GRADE strong recommendation in favor of therapy or diagnostic or prognostic test

This flowchart depicts what can happen when developing an AHA ECC recommendation informed by a GRADE strong recommendation in favor of therapy or a diagnostic or prognostic test. (“ECC” is the acronym for “Emergency Cardiovascular Care.” “GRADE” is an acronym that stands for “Grading of Recommendations Assessment, Development, and Evaluation.”) This flowchart includes four boxes. The box of origin includes the text “GRADE strong recommendation in favor.” From this box, there are arrows leading directly to the three other boxes. A solid arrow labeled “Maybe” points to a box titled “Convert to AHA ECC Class 1 (Strong) Recommendation If Benefit [is substantially greater than] Risk.” The text description states: “Therapy or test is “recommended or indicated, effective or beneficial, should be done.” This applies to therapies or tests that are considered the standard of care or that should generally be provided or used for the vast majority of patients.” Another solid arrow labeled “Maybe” points from the box of origin to another box. This one is titled “Convert to AHA ECC Class 2 A (Moderate) Recommendation If Benefit [is somewhat greater than] Risk.” The text description states: “Therapy or a test is  “probably recommended, is reasonable, can be useful, effective, or beneficial.” It is appropriate for most patients, with some exceptions.” A dashed arrow labeled “Unlikely” leads from the box of origin to the remaining box. It’s titled “Convert to AHA ECC Class 2 B (Weak) Recommendation If Benefit [is greater to or equal than] Risk. The text description states: “Therapy or text “may or might be reasonable or may or might be considered, but other options are acceptable.” The “usefulness or effectiveness is unknown, unclear, or uncertain or will not well established.” This figure is copyright 2015 by the American Heart Association. There is a caption beneath this Figure which reads: “Developing an AHA ECC recommendation that is informed by a GRADE strong recommendation in favor of a therapy or diagnostic or prognostic test.”