Inclusion and Exclusion Criteria for Key Extracorporeal CPR Articles
Study CA Type Inclusion Criteria Exclusion Criteria
Chen, 20081 IHCA Witnessed CA of cardiac origin (elevated cardiac enzymes before CA, sudden collapse without obvious cause, or sudden collapse with pre-existing cardiovascular disease)
  • Age less than 18 years or greater than 75 years
  • Known severe irreversible brain damage
  • Terminal malignancy
No ROSC during first 10 minutes of conventional CPR
  • Traumatic origin with uncontrolled bleeding
  • Postcardiotomy shock with inability to be weaned from cardiopulmonary bypass
Shin, 20112 IHCA
  • Witnessed CA of cardiac origin
  • No ROSC during first 10 minutes of conventional CPR
  • Age less than 18 years or greater than 80 years
  • No sustained (20 minutes or more) ROSC during first 10 minutes of conventional CPR
  • Known severe neurologic damage
  • Current intracranial hemorrhage
  • Terminal malignancy
  • Traumatic origin with uncontrolled bleeding
  • Noncardiac origin* (submersion, drug overdose, asphyxia, exsanguination, sepsis)
  • Irreversible organ failure (liver failure, late stage of adult respiratory distress syndrome, etc)
Lin, 20103 IHCA
  • Witnessed CA of cardiac origin
  • No ROSC during first 10 minutes of conventional CPR
  • Age less than 18 years or greater than 75 years
  • Known severe irreversible brain damage Terminal malignancy
  • Severe trauma
  • Uncontrolled bleeding
Maekawa, 20134 OHCA Witnessed CA of presumed cardiac origin
  • Age less than 16 years
  • Terminal malignancy
No ROSC during first 20 minutes of conventional CPR
  • Poor level of activities of daily living before onset of CA
  • Noncardiac origin (trauma, submersion, hypothermia, drug overdose, asphyxia, exsanguination, intracranial hemorrhage, acute aortic dissection)
Sakamoto, 20145 OHCA
  • VF/pVT on initial ECG
  • CA of presumed cardiac origin on hospital arrival with or without prehospital ROSC
  • Arrival to hospital 45 minutes or less after reception of emergency call or onset of CA
  • No ROSC (1 minute or more of continuing confirmation of pulsation) during first 15 minutes of conventional CPR in hospital
  • Age less than 20 years or 75 years or older
  • Poor level of activities of daily living before onset of CA
  • Noncardiac origin (trauma, drug intoxication, primary cerebral disorders, acute aortic dissection, terminal malignancy)
  • Core body temperature less than 30°C
CA indicates cardiac arrest; CPR, cardiopulmonary resuscitation; ECG, electrocardiogram; IHCA, in-hospital cardiac arrest; OHCA, out-of-hospital cardiac arrest; pVT, pulseless ventricular tachycardia; ROSC, return of spontaneous circulation; and VF, ventricular fibrillation.*Postcardiotomy bleeding considered to be of cardiac origin.

References

  1. Chen YS, Lin JW, Yu HY, Ko WJ, Jerng JS, Chang WT, Chen WJ, Huang SC, Chi NH, Wang CH, Chen LC, Tsai PR, Wang SS, Hwang JJ, Lin FY. Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in- hospital cardiac arrest: an observational study and propensity analysis. Lancet. 2008;372:554–561. doi: 10.1016/S0140-6736(08)60958-7.
  2. Shin TG, Choi JH, Jo IJ, Sim MS, Song HG, Jeong YK, Song YB, Hahn JY, Choi SH, Gwon HC, Jeon ES, Sung K, Kim WS, Lee YT. Extracorporeal cardiopulmonary resuscitation in patients with inhospital cardiac arrest: A comparison with conventional cardiopulmonary resuscitation. Crit Care Med. 2011;39:1–7. doi: 10.1097/CCM.0b013e3181feb339.
  3. Lin JW, Wang MJ, Yu HY, Wang CH, Chang WT, Jerng JS, Huang SC, Chou NK, Chi NH, Ko WJ, Wang YC, Wang SS, Hwang JJ, Lin FY, Chen YS. Comparing the survival between extracorporeal rescue and conventional resuscitation in adult in-hospital cardiac arrests: propen- sity analysis of three-year data. Resuscitation. 2010;81:796–803. doi: 10.1016/j.resuscitation.2010.03.002.
  4. Maekawa K, Tanno K, Hase M, Mori K, Asai Y. Extracorporeal cardio- pulmonary resuscitation for patients with out-of-hospital cardiac arrest of cardiac origin: a propensity-matched study and predictor analysis. Crit Care Med. 2013;41:1186–1196. doi: 10.1097/CCM.0b013e31827ca4c8.
  5. Sakamoto T, Morimura N, Nagao K, Asai Y, Yokota H, Nara S, Hase M, Tahara Y, Atsumi T; SAVE-J Study Group. Extracorporeal cardio- pulmonary resuscitation versus conventional cardiopulmonary resus- citation in adults with out-of-hospital cardiac arrest: a prospective observational study. Resuscitation. 2014;85:762–768. doi: 10.1016/j. resuscitation.2014.01.031.